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New Stroke Injection Drug Set to Revolutionize Treatment in Israel
A new stroke medication, Tenecteplase (TNK), which is administered via a rapid single injection in seconds, is expected to be registered and available in Israel by early 2027. The drug will gradually replace the current standard treatment, Alteplase (tPA), which requires a complex, hour-long intravenous infusion.
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What happened
- 01A new stroke drug, Tenecteplase (TNK), administered via a rapid injection in seconds, is expected to be registered in Israel by early 2027.
- 02TNK will gradually replace Alteplase (tPA), the current standard treatment that requires a complex, hour-long intravenous infusion.
- 03Approved by the FDA in March 2025, TNK dissolves blood clots causing ischemic strokes, which make up about 90% of all strokes.
- 04Clinical studies show TNK is as effective as tPA, with a lower risk of brain hemorrhage and better overall recovery outcomes.
- 05TNK restored blood flow before mechanical catheterization in 22% of patients compared to 10% for tPA, according to Cursorinfo.
- 06In 2023, Israel recorded over 16,000 stroke cases, but only 11% of those patients received clot-busting treatment.
- 07Medical experts emphasize that prompt arrival at the hospital remains critical for saving brain tissue, regardless of the medication used.
Approved by the FDA in March 2025, TNK is designed to dissolve blood clots causing ischemic strokes, which account for approximately 90% of all stroke cases. Clinical studies, including a large meta-analysis of over 7,500 patients published in the journal Neurology in 2024, show that TNK is at least as effective as tPA, offers a lower risk of brain hemorrhage, and leads to statistically higher chances of a good recovery.
The rapid administration of TNK simplifies medical procedures for healthcare teams, particularly for patients requiring subsequent mechanical thrombectomy. According to Cursorinfo, studies show TNK restored blood flow before catheterization in 22% of patients compared to 10% with tPA, and it can speed up patient transfers to specialized stroke centers. In 2023, Israel recorded over 16,000 stroke cases, with only 11% receiving clot-busting treatment, and medical experts emphasize that prompt hospital arrival remains critical to saving brain tissue.
Summarized by baba from the reports of 3 newsrooms. Updated
Latest report: Ynet. Read Ynet’s originalThe coverage
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