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YnetHealth

Late-Life Pregnancy: The Biological Realities Behind the Social Clock

Translated & summarized from Ynet by baba

CenterNeutral tone

Hebrew · 1 newsroom

Women's fertility is significantly impacted by egg age, with chances of pregnancy decreasing and risks of miscarriage and chromosomal abnormalities increasing after 35. Societal trends delay family planning, but the biological clock remains unchanged, with media often highlighting successful later-life births achieved through egg freezing or donation. Egg freezing is available in Israel from age 30, offering a way to preserve fertility, though it does not guarantee a successful pregnancy. The decision between freezing eggs or embryos involves personal considerations and requires sperm for embryo creation.

The story in 6 lines · by baba

  • Fertility is primarily determined by egg age, with risks increasing significantly after 35.
  • Societal trends delay family planning, but biological clocks do not advance.
  • Later-life pregnancies often involve previously frozen eggs or donor eggs.
  • Egg freezing is available in Israel from age 30 to preserve fertility.
  • Egg freezing is not a guarantee of a live birth.
  • Embryo freezing requires sperm and confirms successful fertilization.

Women's fertility is primarily determined by age, specifically the age of their eggs, a fact often overshadowed by societal shifts and media portrayals of later-life pregnancies. While modern life allows women to pursue education and careers before starting families, pushing back the social clock, their biological clock does not similarly advance. Media often highlights celebrity births after age 45, creating an impression that advanced medicine makes delaying childbirth entirely feasible. However, these successes frequently involve eggs frozen at a younger age or donor eggs, as the age of the uterus is distinct from the age of the egg. While a uterus can carry a pregnancy from a younger egg, the ability to create a viable embryo is critically dependent on the egg's age. Women are born with a finite number of eggs that decrease over time. As women age, monthly pregnancy chances decline, miscarriage risks rise, and the likelihood of chromosomally normal embryos diminishes significantly after 35, accelerating thereafter.

To address this, egg freezing offers a way to preserve fertility. Eggs can be retrieved and frozen at a younger biological age for future use. In Israel, non-medical egg freezing is available from age 30, empowering women with more choices. However, egg freezing is not a guarantee of a live birth, as not all frozen eggs survive, fertilize, develop into viable embryos, or implant successfully.

Some women opt for embryo freezing over egg freezing, or a combination. Embryo freezing has the advantage of confirming which eggs have successfully fertilized and developed. This method, however, requires sperm from a partner or donor and involves personal considerations, such as waiting for a partner. Ultimately, while egg freezing doesn't stop time, it provides peace of mind for women navigating a modern social timeline that is out of sync with their biological clock, according to Dr. Ronit Almog, an expert in gynecology, obstetrics, and fertility treatments at Tel Aviv Sourasky Medical Center.

YnetCentre · Rishon LeZion

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