Tel Aviv-Jaffa ranked fourth in Startup Genome’s annual global startup ecosystem list for the second year in a row, behind Silicon Valley, New York and London. The city’s ecosystem was valued at $250 billion, according to the research and consulting firm’s Global Startup Ecosystem Report, which was released today at the VivaTech conference in Paris.
Startup Genome said the report is based on the world’s largest startup database, analyzing more than 5.5 million companies across over 350 innovation and entrepreneurship environments. It tracks global startup trends and ranks the 40 leading cities worldwide. The firm’s ecosystem value metric measures economic impact through startup exits and valuations.
The report said Tel Aviv’s ecosystem generated $250.3 billion in value from data collected between July 1, 2023 and December 31, 2025, a 162% increase from the previous report in 2021. The main engines of the city’s startup growth are artificial intelligence, big data, analytics, cybersecurity and life sciences. Tel Aviv ranked fifth worldwide in AI startups and placed in the global top 10 in research and development, human capital strength, and performance.
Startup Genome founder and president Marc Penzel said Tel Aviv stands out for “the concentrated depth of talent and innovation” driving it, especially in AI, big data, cyber and life sciences. He added that holding fourth place year after year shows an ecosystem with “a sustained competitive advantage” in sectors shaping the global economy.
Tel Aviv City Hall runs Tel Aviv Global, also called City of the World, which works to strengthen and promote the city’s innovation ecosystem from early-stage ventures to growth companies and multinationals. Mayor Ron Huldai said innovation in Tel Aviv-Jaffa is “not just an industry” but part of the city’s identity and way of life, and that the municipality is continuing to support Israeli startups and major international companies, especially amid global changes and the AI revolution.
